(HealthDay)—Swedish massage therapy (SMT) is associated with clinically significant relief from cancer-related fatigue (CRF) in breast cancer survivors, according to a study published online Oct. 17 in Cancer. Becky Kinkead, Ph.D., from Emory University in Atlanta, and colleagues evaluated the efficacy of weekly SMT compared with an active control condition (light touch [LT]) and waitlist control (WLC) in an early-phase, randomized, single-masked, six-week investigation. They enrolled 66 female stage 0-III breast cancer survivors (age range, 32-72 years) who had received surgery plus radiation and/or chemotherapy/chemoprevention with CRF (Brief Fatigue Inventory >25). The researchers found that SMT resulted in a mean six-week reduction in Multidimensional Fatigue Inventory total scores of -16.5 versus -8.06 for LT and an increase of 5.88 points for WLC. The mean reduction in PROMIS Fatigue scores was -5.49 points for SMT versus -3.24 points for LT and -0.06 points for WLC. These results were not accounted for by the higher credibility, expectancy, and preference for SMT versus LT. “This finding suggests that 6 weeks of a safe, widely accepted manual intervention causes a significant reduction in fatigue, a debilitating sequela for cancer survivors,” conclude the authors.